EFFECTS OF CIMETIDINE ON THE PHARMACOKINETICS OF MEFLOQUINE, PROGUANIL AND QUININE IN HEALTHY SUBJECTS AND IN PEPTIC ULCER PATIENTS

EFFECTS OF CIMETIDINE ON THE PHARMACOKINETICS OF MEFLOQUINE, PROGUANIL AND QUININE IN HEALTHY SUBJECTS AND IN PEPTIC ULCER PATIENTS

TABLE OF CONTENT
Title page- – – – – – – – – i
Approval page – – – – – – – -ii
Dedication – – – – – – – – -iii
Acknowledgement – – – – – – – -iv
Abstract – – – – – – – – – -v
Table of content – – – – – – – -vi

CHAPTER ONE
INTRODUCTION – – – – – – – -1
1.0 Background of the study – – – – -1
1.1 Statement of the problem – – – – -5
1.2 Purpose of the study – – – – – -6
1.3 Significance of the study – – – – -8
1.4 Research questions – – – – – -9
1.5 Scope of the study – – – – – – -10

CHAPTER TWO

LITERATURE REVIEW – – – – – – -11

CHAPTER THREE

Research methodology – – – – – – -39
Design of study – – – – – – – -40
Area of study – – – – – – – – -40
Population of the study – – – – – – -41
Sample and sampling techniques – – – – -41
Instrument for data collection – – – – -41
Method of data collection – – – – – -42
Method of data analysis – – – – – – -43

CHAPTER FOUR

Presentation, analysis and interpretation of data – -48
Discussion of findings – – – – – – -56

CHAPTER FIVE

Summary of findings – – – – – – -60
Conclusion – – – – – – – – -61
Recommendations – – – – – – – -62
Suggestions for further research – – – – -64
References – – – – – – – – -65
Appendix I – – – – — – – – -68
Questionnaire. – – – – – – – -69

EFFECTS OF CIMETIDINE ON THE PHARMACOKINETICS OF MEFLOQUINE, PROGUANIL AND QUININE IN HEALTHY SUBJECTS AND IN PEPTIC ULCER PATIENTS